The fatty acid derivative MOCOAT-S is used to enhance the stability of oil-base drilling fluids. When used in combination with the primary emulsifier MOEMUL-S, it can significantly improve the stability of oil-base drilling fluids in a wide range of oil-water ratio (40/60 ~ 10/90), and has good stability to the oil-base drilling fluids system. It has good emulsification property with the main emulsifier and other treating.